Boston’s 41 most important VCs, according to other investors

• Before Silicon Valley, early venture capitalists hunted startup founders in Boston.
• Established companies like General Catalyst, Bessemer, and Accomplice call the city home.
• This list features Boston’s best and brightest investors, from directors to general partners.

Boston Route 128 was the original Sand Hill route.

In the 1960s and 1970s, the four-lane highway bypassed the city’s myriad universities and research centers to the suburbs, where high-tech startups rented offices in cheaper zip codes. Early venture capitalists like General Catalyst and Bessemer drove founders and wealth there overnight. And in the 1970s, the rapid growth of local tech giants like Digital Equipment Corporation and Raytheon cemented Boston’s status as a global technology hub.

Soon, rival technology hubs overtook the East Coast city. Still, Boston remains a hotbed of venture capital investment, especially for health tech companies. In 2021, a banner year for tech, venture capitalists nationwide invested $34.9 billion in Boston startups, making the region the fourth-largest market for investment, after the Bay Area, New York. and Los Angeles, according to PitchBook data.

The Boston area boasts a number of savvy investors, albeit under the radar, as residents. We asked venture capitalists across the country about Boston investors to know. We’ve also referenced our previous reports on top seed investors to find more choices.

Let us know who we missed by contacting Venture Capital Startups and Correspondent Melia Russell at [email protected].